Cortisone Injection

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Dr Robert Ong of Medical Aesthetics.
Written By: Dr Robert Ong (MBBS, GDFP (Dermatology), Member - American Academy of Aesthetic Medicine)
Last updated: Aug 14, 2025

What Is a Cortisone Injection?

Close-up of cortisone injection into acne nodule showing dermatological treatment in Singapore.

A cortisone injection is a medical procedure that involves injecting a corticosteroid directly into inflamed or swollen areas to reduce inflammation and promote healing.

In dermatology, cortisone injections are commonly used to manage inflammatory skin conditions such as severe acne lesions, particularly cystic or nodular acne.

If you are dealing with deep, painful breakouts, you may find they affect more than just your skin. They can also take a toll on your self-esteem and emotional well-being.

At Medical Aesthetics, we offer cortisone injections from $109 to help manage severe acne, providing timely relief from inflammation while supporting clearer skin and renewed confidence.

How Do Cortisone Injections Work for Acne?

Cortisone injections work by rapidly reducing inflammation and suppressing the immune response in acne lesions. This helps relieve swelling and tenderness, with visible improvement often seen within a few days.

When used early for more severe acne, this treatment may also lower the risk of scarring.

Who Might Benefit From a Cortisone Injection?

Close-up of Asian woman with cystic acne showing red nodules on cheek before cortisone injection.

Cortisone injections may be suitable for individuals with painful, inflamed acne lesions that do not respond well to topical or oral treatments. They are most often considered for:

  • Cystic acne that is deep, tender and slow to resolve.
  • Nodular acne with persistent swelling.
  • Single or a few active lesions that require targeted relief.
  • Acne flare-ups before important events, such as weddings, job interviews, photoshoots, or public appearances, where a clearer appearance is desired.

This treatment is typically recommended on a case-by-case basis by a qualified medical professional, based on the type of lesion, your medical history and how your skin has responded to previous treatments.

What to Expect During the Procedure

A cortisone injection is a quick in-clinic procedure that typically takes only a few minutes. The process generally involves:

  1. Cleansing the skin around the lesion with an antiseptic.
  2. Injecting a small amount of corticosteroid directly into the lesion using a fine needle. You may feel minimal discomfort, often described as a brief pinch or sting.

There is usually no downtime, and you can return to your normal activities immediately after the injection.

How Long Does Cortisone Injection for Acne Take to Work?

Visible improvement from a cortisone injection typically begins within 24 to 72 hours. The treated lesion often becomes less swollen, red and painful, and may flatten noticeably as the inflammation subsides.

However, individual responses can vary depending on factors such as the severity of the lesion, the type of corticosteroid used and how your skin responds to the treatment.

Are There Any Cortisone Side Effects or Risks?

Aesthetic doctor injecting cortisone for acne management with potential localised side effects.

Cortisone injections are generally regarded as well-tolerated when administered by qualified practitioners. However, like all medical procedures, they can carry potential side effects, which may include:

  • Indentation if the acne lesion is close to the surface.
  • Temporary lightening of the skin (hypopigmentation), particularly in darker skin tones.
  • Skin thinning (atrophy) at the injection site.
  • Recurrence of acne if the underlying causes are not addressed.

Although uncommon, allergic reactions such as localised redness, itching, or swelling can occur. Seek prompt medical attention if you experience these symptoms.

The likelihood of these side effects can depend on factors such as dosage, injection depth, and individual skin characteristics.

A consultation with our doctor can help assess whether this treatment is appropriate for your skin and minimise potential risks.

How Often Can You Get Cortisone Injections?

Cortisone injections are spaced out to minimise the risk of cumulative side effects, and are typically limited to one injection per lesion every few weeks.

Your doctor will advise on the appropriate frequency based on your skin condition and treatment needs.

Can Cortisone Injections Be Combined With Other Acne Treatments?

Asian woman getting chemical peel treatment demonstrating acne management with combined therapies.

Cortisone injections are often used together with other acne treatments as part of a broader management plan. Depending on your skin condition, your doctor may recommend combining cortisone injections with:

  • Topical treatments such as retinoids or antibiotics for ongoing acne control.
  • Oral medications including antibiotics or hormonal therapy to target underlying causes.
  • In-clinic procedures such as chemical peels or laser treatments for maintenance and prevention.
  • Lifestyle changes such as a consistent skincare routine, stress management, and avoiding triggers like picking or certain foods.

A combined approach helps manage acne more effectively and reduce the need for repeated steroid injections.

Cortisone Injection Treatment: Before and After Photos

Owing to the regulations of The Ministry of Health (MOH), we are unable to publish before and after photos on our website. However, you may view these photos during your consultation with our doctor to understand more about the treatment you seek.

Why Choose Dr Robert Ong's Cortisone Injection Treatment in Singapore?

The Medical Aesthetics Track Record

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Patients Consulted Since 2002

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Years of Experience

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Google Reviews

Experienced & Friendly Doctor

Dr Robert Ong listens attentively to your concerns and patiently discusses with you the appropriate treatment options, based on over 20 years of medical and aesthetics experience.

Affordable Treatments

We are priced competitively and affordably. We also have a variety of treatment options depending on your budget and requirements.

Safe & Effective Results

Our treatment options are safe, effective and promotes natural healing for your skin. We strive to keep your experience a comfortable one and will minimize any pain or discomfort, if any.

Cortisone Injection Cost in Singapore

At Medical Aesthetics, we offer cortisone injections along with a range of treatments to help manage severe acne. Pricing details are outlined below:

Treatment Price*
Consultation From $38.15 to $70.85
Cortisone Acne Injection From $109
Oral Antibiotics From $2.40 / tablet
Retinoid From $21.80
Antibiotic Gel From $38.15
Chemical Peel From $114.45
Fractional CO2 Laser From $436
Laser Soft Peel From $436

*Prices are NETT and inclusive of GST.
All patients are required to undergo a consultation with our doctor to assess his or her suitability for the relevant treatment(s).

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Frequently Asked Questions

Allergic reactions to cortisone injections are uncommon but can occur in rare cases. These reactions may result from preservatives or other components in the injection rather than the corticosteroid itself. Symptoms can include local irritation, itching, or rash, while severe reactions are rare but possible. It is advisable to inform your doctor if you have a history of allergies to injectable medications or any previous reaction to steroids.

Cortisone injections for acne usually involve only minimal discomfort, often described as a brief pinch or sting during the injection. The procedure is performed with a fine needle and typically takes only a few minutes.

Cortisone injections typically begin to reduce swelling, redness, and tenderness within 24 to 72 hours. Response time can vary depending on factors such as the severity of the lesion, the type of corticosteroid used, and how your skin responds to inflammation. Consulting your doctor can help determine what to expect based on your specific acne presentation.

The effects of a cortisone injection can last from several days to a few weeks, depending on the severity of the lesion and individual skin response. While inflammation may subside quickly, long-term acne control may still require additional treatments.

Cortisone injections can provide rapid relief for inflamed acne lesions and may help reduce the risk of scarring when used early. However, potential drawbacks include skin thinning, hypopigmentation, or indentation, particularly if the lesion is near the surface. They are not intended for treating widespread acne and are most suitable for isolated, severe spots. It is advisable to consult your doctor to assess whether the benefits outweigh the risks for your skin condition.

A general practitioner (GP) with relevant training may administer cortisone injections for acne, though availability can vary. At Medical Aesthetics, we offer cortisone injections from $109, along with a full range of acne treatments including topical and oral medications, as well as in-clinic procedures such as chemical peels and laser therapies.

At Medical Aesthetics, a cortisone injection/shot for acne starts from $109 NETT, inclusive of GST. A consultation is required before treatment and is priced from $38.15 to $70.85. We also offer other treatments to help manage severe acne depending on your skin condition, including topical or oral medications and in-clinic procedures such as chemical peels and laser therapy.

Cortisone injections are commonly used to reduce inflammation in severe acne lesions and can lead to visible improvement within a few days. They are often considered worthwhile for deep cystic or nodular acne, particularly when fast relief is desired. However, they are not a long-term solution and are most effective when used as part of a broader acne treatment plan. Consulting a doctor can help determine the most suitable approach for your skin condition.

Cortisone injections may not be suitable for individuals with skin infections at the injection site, known allergies to corticosteroids, or certain systemic conditions. Those prone to skin thinning, pigmentation changes, or recurrent acne flares may also require extra caution. It is important to inform your doctor of your full medical history to help determine whether cortisone injections are appropriate for your skin and overall health profile.